When glutathione is very high, the usual cause is liver damage.
In the acute stage of various viral hepatitis and drug toxic hepatocyte necrosis, ghrelin can be released into the blood in large amounts, so it is an important indicator for diagnosing viral hepatitis and toxic hepatitis.
The diagnosis of hepatitis is generally made by a glutathione transaminase level greater than 2.5 times the upper limit of normal and persistently abnormal for more than half a month. Serum ALT measurement has the characteristics of high sensitivity and low specificity for the diagnosis of hepatitis.
Many extrahepatic factors can also cause elevated GLTA, such as malnutrition, alcoholism, cardiomyopathy, cerebrovascular disease, or due to certain drugs that are toxic to the liver, such as isoniazid, chlorpromazine, salicylic acid preparations, organophosphates, etc., which can also cause elevated serum mid-glutamic transaminase activity.
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